Von Willebrand Disease (VWD) and Heavy Menstrual Bleeding

Participants must be available during two consecutive menstrual cycles and be willing to:

• Estimate blood loss daily during menstruation
• Measure menstruation duration
• Assess quality of life 
• Use a non-invasive neurostimulation device from the comfort of their home during menstruation

Participate from the comfort of your home.

Five Liters will ship the Volta wearable neurostimulation device and instructions for use directly to qualified participants. Data will be self-reported and aggregated into the overall clinical trial results. The first set of measures will be taken during the first cycle under normal conditions, and the second set of measures will be taken during the second cycle with added daily neurostimulation.

● You will be compensated for your time.

● Our Ultimate Goal: To offer the 3 million individuals in
the U.S. affected by VWD and heavy menstrual
bleeding a safer, non-pharmaceutical, and non-
invasive solution for an improved quality of life.
● Help Support a Brighter Future for Women With von
Willebrand Disease.

You may be eligible to support this pioneering clinical trial if you:

• Are diagnosed with von Willebrand Disease Type 1 
• Have a history of heavy menstrual bleeding
• Are Between the ages of 18-45
• Have not been pregnant at any point in the past 3 months
• Are not currently lactating
• Do not have a history of tobacco use, ingested nicotine via smoking, vaping, smokeless tobacco, or nicotine patches in the past 3 months
• Do not have a pacemaker, cochlear implant, or implanted neurostimulation system
• Have reliable access to an internet enabled device